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Is fibromyalgia genetic?

Posted in Fibromyalgia Information. on Sunday, July 27th, 2008 by Sarakastic
Jul 27

This was one of the first questions I had after I was diagnosed. None of my other family member’s have fibromyalgia. Unfortunately, the doctor didn’t have a straight answer for me. I was just reading up on the subject again & was frustrated by all of the differing answers. I try not to worry but every time a family member says they don’t feel well but can’t describe exactly what is wrong, I freak out. What do you think? Is fibromyalgia genetic?

6 Comments

  1. Swords (1 comments.) on July 29th, 2008

    Researchers also have taken the fact that fibromyalgia is more common in women than men and suggested that the sex hormone estrogen is involved. However, little correlation has been discovered. It also has been suggested that the lower levels of testosterone in women than in men is more likely involved since testosterone is involved in building muscle strength.

  2. Sandy/Fighting Fatigue (1 comments.) on August 2nd, 2008

    You’ve been tagged! The post will be live Saturday, 8/2.

    http://icdisease.today.com/2008/08/02/tag-its-my-turn-to-be-it/

  3. nobe (1 comments.) on August 3rd, 2008

    i have to research fibromyalgia on wikipedia. im not really familiar with it.

    I got your site from Randa Clay It’s amazing, a lot of people are already a part of this “u comment i follow” movement. I’m sure glad I am!

    Sincerely,
    Nobe

    I have two blogs following the movement. Yipee! :)

    love letters to my infant son - http://www.deariago.blogspot.com
    my favorite internet things - http://www.nobe112681.blogspot.com

  4. Love Text Messages (1 comments.) on August 12th, 2008

    The relationship between children and parents having either fibromyalgia or other pain related problems has led some researchers to suggest a genetic cause. Particular genetic markers have been mentioned, but those markers have been different in different studies.

  5. Motorcycle Jackets (1 comments.) on August 21st, 2008

    Genetic linkage analysis of multicase families with fibromyalgia syndrome.Based on the reports of familial aggregation of fibromyalgia (FM) syndrome, we investigated its possible genetic linkage to HLA by studying multicase families. METHODS: Forty Caucasian multicase families with a diagnosis of FM (American College of Rheumatology criteria) in 2 or more first degree relatives were investigated. Eighty-five affected and 21 unaffected members of 41 sibships were studied. Depression symptomology was assessed by Zung Self-rating Depression Scale (SDS). HLA typing was performed for A, B, and DRB 1 alleles, and haplotypes were determined with no knowledge of the subject’s diagnosis. We investigated genetic linkage to the HLA region by evaluating sibships in multicase families. RESULTS: Sibship analysis showed significant genetic linkage of FM to the HLA region (p = 0.028). Subgroup analysis was also performed for 17 families where the proband was also noted to have depression (with an SDS index value > or =60). We found that the presence of depression did not influence the observed results (p = 0.22). CONCLUSION:. Our study of 40 multicase families confirms existence of a possible gene for FM that is linked with the HLA region. Our results should be regarded as preliminary and their independent confirmation by other studies is warranted.”

  6. Cylapril (2 comments.) on October 27th, 2008

    I can imagine the fatigue your going through because of the indecisiveness of the doctor.



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